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OARSI Hand OA Discussion Group - Shared screen with speaker view
Dan Lemyre
20:05
Please be aware this session is being recorded.
Garrett Bullock
25:36
Can send chat box to me directly since I am monitoring this call
Tonia Vincent
28:02
What about pathogenic mechanisms?
Dominic Furniss
28:06
What about molecular studies
Fiona Watt
29:21
How do the EULAR treatment guidelines fit in?
Krysia Dziedzic
29:23
It would good to know how well we've managed to change policy and practice with our existing guidelines before making new ones
Fiona Watt
29:30
Published 2019
joy macdermid
29:38
agree important types of studies missing, establishing phenotypes has to precede trials and trails have to precede guidelines
Dominic Furniss
29:57
How many abstained?
Jennifer Nichols
30:04
I concur. We need the basic science studies to guide the trials.
joy macdermid
30:27
clinical phenotypes studies, mechanism of disability not just disease
Vincenzo Nelli
30:37
5 did not vote.
Mick Jurynec
30:37
I agree as well with Tonia and Dominic
Thomas Perry
30:48
There is a chicken and egg situation. Need definitions of hand OA.
Dominic Furniss
30:50
5 is 30%?
Nidhi Sofat
30:52
If trials are looked at it could be a starting point to see what has worked and what hasn’t in the past
Dan Lemyre
33:40
5/40 = 12.5% abstained (2 of the 40 are staff) 3/38= 7.9%
Dominic Furniss
34:03
@Dan - thanks
Martin Englund
39:30
Post traumatic phenotype
joy macdermid
39:42
pain with stiffness, pain with instability, etc
Jeremie Sellam
39:59
There is also early versus established HOA
Fiona Watt
40:06
Longevity/trajectories, poorly defined right now
Fiona Watt
41:16
Nodal??
Ruth Wittoek
41:59
thumb base vs. IP joint, and within IP, erosive vs. non erosive
joy macdermid
42:00
there may need to a multi-dimensional phenotype where we characterize prevalence of more detailed phenotypes based on multiple factors mentioned
Thomas Perry
43:25
Clustering of joint involvement across /within digits
Krysia Dziedzic
50:51
Apologies I can't stay
Tonia Vincent
51:33
Sorry. Would love to stay for longer but have another meeting to go to. Look for to catching up with the recording. Tonia
joy macdermid
52:32
difference in difference in disease phenotypes and functional phenotypes given the importance of the hand to hand function
joy macdermid
54:10
thumb is about 50% of hand "function" and thus auscan scores more affected when thumb involved, but disease might be more dimilar
Mick Jurynec
56:05
We have sequenced over 40 erosive OA families and are finding gene variants that are also found in other forms of OA (hip/knee/foot). We are currently sequencing CMC families and IP joint as well.
Ruth Wittoek
01:17:02
Anatomical phase scoring system (as indicated by Ida) used for identification of erosive hand OA; more recent scoring system developped in our university (GUSS) , only being developped for RCTs
Ali Mobasheri
01:20:45
Good session everyone, many thanks for the opportunity to join the discussion
Ruth Wittoek
01:21:40
sorry, my battery was completely low...
Mick Jurynec
01:21:48
Thanks to the speakers for great talks
Francisco Blanco
01:22:17
Thanks for this great sesión, congratulation
Jeremie Sellam
01:22:35
Thanks for this session, very interesting
Li Zeng
01:22:48
What is known on the kind of physical activities affecting hand OA?
Ali Mobasheri
01:23:22
I suggest that Nigel buys everyone a round of drinks at the bar this time next year!
Martin Englund
01:23:35
Great session!Just don't forget the potential role of occupational load and singel or repetetive trauma
Fiona Watt
01:23:53
Great idea to have another meeting (drinks on Nigel!)
Catherine Hill
01:24:23
Excellent Session. Thank you
Dominic Furniss
01:24:28
Well done organisers and speakers
Augustin Latourte
01:24:38
Great session ! Thank you
Martin Englund
01:24:38
well organized and well presented! Congrats
Fiona Watt
01:24:39
Thanks for organising this, Kari.
Ruth Wittoek
01:24:41
Great session! Good day/evening
Ida Haugen
01:24:47
Well organised, Kari and Nigel!
Thomas Perry
01:24:49
Great job !
Pavlos Bobos
01:25:24
Thanks everyone